Mangosteen Extract: Benefits, Side Effects & Dosage

What is Mangosteen Extract?

Mangosteen extract is derived from the tropical fruit mangosteen — a delicate, dark purple fruit found in Thailand, Malaysia, Singapore, Vietnam and Indonesia (x). Because of its high levels of special antioxidants, known as xanthones, it is uniquely different than other tropical fruits. Most importantly, the fruit’s juice, rind, twig and bark are all used for medicinal purposes (x).

Nutritional Benefits of Mangosteen

Given its exceptional nutritional value, it is not surprising to hear people refer to it as “the Queen” of tropical fruits. First of all, mangosteen has played a significant role in traditional Asian medicine since the 18th century. It contains xanthones that reduce oxidative stress caused by free radicals. Secondly, Xanothones contain vitamin C, which strengthens the immune system. Finally, mangosteen offers a rich source of dietary fibers, vitamins C, B1, B3 and B9.

What is Extracted?

The rind contains the bioactive compounds alpha-mangostin, beta-mangostin, garcinone B and garcinone E, which are all called xanthones (x, x). In fact, people in Southeast Asia have been using the rind of mangosteen for centuries to treat a number of conditions including diarrhea, urinary tract infections (UTIs), cancer and intestinal infections (x). As “biologically active” plant-derived compounds, xanthones protect the body from various illnesses and may help prevent disease.

Medicinal Benefits

The rind of the mangosteen contains phenolic acid and flavonoids, which possess powerful medicinal properties (x, x). In fact, a number of studies have concluded that mangosteen contains anti-inflammatory, antifungal, antimicrobial and antiseptic properties (x).

Benefits of Mangosteen Extract

Helps Treat Diarrhea and Improves Digestion

This well-known tropical fruit may help maintain intestinal health and has been an effective treatment for noninfectious diarrhea, dysentary, inflammation and other conditions (x, x). In fact, mangosteen fruit offers relief for individuals experiencing stomach disorders.

Beneficial to Skin

Mangosteen contains xanthones that suppress the production of cytokines which trigger cystic acne and other blemishes. Additionally, this tropical fruit is rich in polyphenols which helps your body fight illness. Coupled with vitamin C, it has the profound ability to purify, cleanse and nourish the skin.

Helps Treat Urinary Tract Infections (UTIs)

Mangosteen contains bioactive compounds known as xanthones that have proven to have positive effects on urinary tract infections. To put it simply, mangosteen contains antibacterial properties that help cleanse the digestive tract (x).

Potentially Treat Cancer

Mangosteen is one of earth’s most natural sources of powerful antioxidants. In fact, extracts from xanthone have proven to have anti-colon cancer effects in vitro and in vivo, as shown in a 2012 study (x). Moreover, the therapeutic compounds of mangosteen are being studied as potential treatments for breast, lung and colon cancer.

Aids in Lowering Blood Sugar

Supplementing with mangosteen extract may help stabilize blood sugar and improve diabetes by inhibiting enzymes that cause the breakdown of starches into glucose (x). The antioxidants contained in mangosteen may help to maintain blood glucose levels and prevent complications.

Helps Promote Heart Health

As a rich source of potassium, copper, magnesium and manganese, (x) mangosteen can help regulate your blood pressure and may be helpful in reducing the risk of stroke or myocardial infarction. In short, it is ideal for cardiovascular health and may decrease your risk of having a heart attack or stroke.

May Support a Healthy Immune Response

Mangosteen is packed with a multitude of minerals and vitamins that may prevent many illnesses from striking in the first place (x). Most importantly, it protects the body from various health ailments that could weaken the immune system.

Mangosteen Benefits

Mangosteen Extract Supplement

Mangosteen is available in various forms, including powders. When taking mangosteen powder, take 3,000 mg (1 tsp) to 6,000 mg (2 tsp) daily, or as directed by a physician. Not only is it highly nutritious, but it is a novel ingredient for use in a variety of culinary based products. It can be added to enhance ice-creams, sorbets, yogurts, smoothies, cocktails and salad dressings.

Mangosteen Dosage and Side Effects

In a case reported by the Memorial Sloan-Kettering Cancer Center, severe lactic acidosis occurred after daily use of mangosteen juice for 12 months. Symptoms of this condition include nausea, weakness and stomach discomfort. If left untreated, this condition may cause life-threatening medical complications (x, x).

The Bottom Line

In conclusion, mangosteen can be helpful in treating disease and a variety of health conditions. The xanthones contained in mangosteen possess antioxidant, anti-inflammatory, antibacterial and antiviral properties. However, side effects of an oral mangosteen extract include tiredness, constipation, dry throat, headache and indigestion. See a doctor if any extreme side effects occur.

Author: James D