l-glutamic acid

L-Glutamic Acid. Provides Support for Endurance, Memory, & Digestion.

Updated: 12/18/23

Are you looking for an all-natural and powerful supplement to enhance your overall health? Look no further than L-Glutamic Acid! This essential acid is naturally found in many of the foods we eat, yet our bodies don’t produce it on their own. By taking a daily supplement, you can reap the many benefits that L-glutamic acid has to offer. From supporting endurance and digestion to boosting memory retention, this amino acid provides a wealth of benefits that are sure to benefit any health conscious individual looking for an extra boost throughout their day. Keep reading if you want more information on how adding this essential nutrient into your diet can help improve your mental and physical wellness.

L-glutamic acid is a staple in many preworkout blends. But it doesn’t just kick your workout up a notch (or twenty). It boasts multiple health benefits and could help with everything from your fitness to your digestion and brain function.

What is L-Glutamic Acid?

L-Glutamic Acid is a non-essential amino acid, which means that our body can produce it on its own. It is also considered one of the building blocks of protein and is found naturally in various food sources, including dairy, poultry, fish, and eggs. L-Glutamic Acid is also a crucial neurotransmitter that is responsible for maintaining a healthy brain and central nervous system.

Apart from being found in the food we eat, L-Glutamic Acid is also produced by the human body. Our body can convert glutamine, another essential amino acid found in protein-rich foods, into L-Glutamic Acid. Additionally, L-Glutamic Acid can also be formed from the breakdown of other amino acids, specifically arginine, and proline.

L-Glutamic Acid is mainly responsible for neurotransmission, which is the process of transmitting nerve impulses from one neuron to another. This process helps our body with muscle movements, cognition, memory, and maintaining a healthy nervous system. When L-Glutamic Acid is released, it attaches itself to receptors on a receiving neuron, which then triggers a response. This response can vary from activating muscle movements to affecting our mood and learning abilities.

L-Glutamic Acid Benefits

May Boost Your Brain Function

One of the most profound benefits is its ability to improve cognitive function. This amino acid is a precursor to glutamate, which is the most abundant neurotransmitter in your brain. L-Glutamic acid is responsible for carrying crucial messages between neurons, which is vital for learning and memory. L-Glutamic acid helps produce more glutamate in the brain, which leads to better focus, mental clarity, and improved memory.

May Reduce Stress and Anxiety

It can help reduce stress and anxiety by regulating the production of cortisol, the stress hormone. This amino acid can also help improve sleep quality, allowing you to wake up feeling refreshed and rejuvenated.

May Strengthen Your Immune System

Another essential benefit is its ability to boost your immune system. It produces glutathione, one of the most potent antioxidants in your body. This antioxidant helps reduce oxidative stress, which can damage your immune system. It also helps your body ward off harmful pathogens and diseases.

Promotes Healthy Skin

It is an essential component of collagen, a protein that makes up the skin, hair, and nails. Collagen production declines with age, leading to wrinkles, sagging skin, and other signs of aging. By taking L-glutamic acid supplements, you can help boost collagen production, leading to firmer, more youthful-looking skin.

Supports Muscle Growth

It is also essential for building muscle. It is in protein synthesis, which is vital for muscle growth and repair. L-glutamic acid helps transport amino acids to where they are needed in your body. This amino acid can help you build and maintain muscle mass, especially if you are physically active.

Promotes Digestive Health

It can also benefit your gut health. It is in the production of stomach acid, which is vital for breaking down food and absorbing nutrients. This amino acid also helps heal the lining of your gut, preventing inflammation and conditions like leaky gut.

May Aid in Weight Loss

Are you struggling to shed those extra pounds? It can help. This amino acid can increase your metabolic rate, which means you burn calories faster. It also reduces feelings of hunger and cravings, which can help you stick to a healthy diet.

l-glutamic acid benefits

L-Glutamic Acid Side Effects

Digestive Issues

A common side effect of an excessive intake is digestive issues. This can manifest as bloating, gas, and diarrhea. If you notice these symptoms, it is an advisement to decrease your intake of glutamate-containing foods and supplements.


Another side effect of excess is headaches. In some people, high levels of glutamate can trigger migraines or other types of headaches. This occurs because L-glutamic acid is an excitatory neurotransmitter that can overstimulate the brain.


Side effects might also include hypertension, or high blood pressure. The reason for this is that excess glutamate can cause the blood vessels to constrict, leading to higher blood pressure.

Allergic Reactions

Although rare, allergic reactions to L-glutamic acid can occur. These can range from mild itching and swelling to severe anaphylactic shock.

Harmful to People with Certain Conditions

Lastly, people with certain medical conditions, such as kidney and liver diseases, should avoid excessive glutamate intake. This is because excess glutamate can put additional strain on these organs, leading to further health complications.

L-glutamic acid vs L-glutamine

L-Glutamine  is a non-essential amino acid that synthesizes in the body. It is in food sources such as meats, dairy, and certain legumes. L-glutamine is essential for the immune system function, nitrogen transport, and cell division. It is common as a supplement for athletes and bodybuilders to aid in muscle recovery and improve athletic performance.

One of the main differences between L-glutamic acid and L-glutamine is their functions in the body. L-glutamine is important for immune system function and muscle recovery, while L-glutamic acid is more in protein synthesis and metabolism. Additionally, L-glutamine is more common as a supplement for fitness enthusiasts, while L-glutamic acid is in use more in the food industry for flavor enhancement.

Both L-glutamic acid and L-glutamine have benefits for the body. L-glutamic acid is in protein synthesis and can aid in the metabolism of fats and sugars. L-glutamine can improve immune system function and aid in muscle recovery. However, there are also potential side effects to keep in mind. It in high doses may cause headaches, while L-glutamine in high doses may cause gastrointestinal distress.

Glutamic Acid Side Effects and Dosage

You can generally find glutamate supplements available as l-glutamic acid powder. If you opt for this form, take 4000 milligrams once a day, or as otherwise directed by a physician.

Glutamic acid HCL powder is another popular glutamate supplement. It contains hydrochloric acid (HCL) to help it dissolve in liquids and to ease digestion.

The Bottom Line

L-Glutamic Acid is undoubtedly one of the most versatile and beneficial amino acids out there. From improving immune function to promoting muscle growth, the benefits are endless. And, since it’s a naturally occurring amino acid, you can rest assured that you’re taking a safe and effective supplement. If you’re looking for a way to improve your overall well-being, it is definitely worth considering. Talk to your doctor or health care provider to see if it’s right for you.

While there are many benefits to incorporating L-glutamic acid into your diet, it is essential to take the potential side effects into account. Do not hesitate to consult a healthcare professional before including glutamate-rich foods or supplements into your diet. Moderation is key, and a diverse diet with a variety of essential amino acids will always be the healthiest and safest option.

The statements in this article have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Author: James D