Shiso Perilla Extract. Nature’s Support For Multiple Health Benefits

Updated: 11/7/23

Are you looking for new ways to support your health and wellbeing? Plants can offer some of the most powerful superfoods and Shiso Perilla seeds are certainly one of them! For centuries, Shiso plants (or Perilla frutescens) have been revered by many cultures with their leaves used in cooking as well as various medicinal purposes. But it’s only recently that these incredibly small yet mightly seeds have begun to gain worldwide attention due to their impressive health benefits. From boosting brain power, promoting healthy skin cells growth, and improving immune function – here is a closer look at how adding shiso perilla seeds into your diet could help bolster overall wellness.

What is Shiso Perilla?

Shiso Perilla is a type of herb that is native to parts of Asia – particularly China, Japan, and Korea. It has been used in traditional Chinese and Korean medicine for centuries because of its potent antioxidant, anti-inflammatory, and anti-cancer properties. Shiso Perilla is also highly valued for its culinary uses and is commonly used to season salads, sushi, and other Japanese/Korean dishes. The herb has a distinctive and delicious flavor, which is sort of a mix between basil, mint, and anise, and can be enjoyed fresh or dried.

The plant has two main types: purple-leafed and green-leafed. It can grow to a height between 60 and 90 centimeters. This plant is highly resilient and it can grow on a wide range of soil types, including gravel, sand and loam. The plant features slightly square, free branched stems. It  is a bushy shrub in the mint family.

Shiso perilla juice is a popular refreshment in many parts of the globe. Mixing it into juice is a great way to incorporate shiso perilla into a daily diet or health regimen. The leafy stems from shiso perilla can also make refreshing teas. However, dried leaf stems often make better tasting and more aromatic tea than fresh stems. Shiso perilla leaves also make an excellent garnish and they are popular ingredients in Asian cuisine. The leaves make tasty soups and salads and they are also common in sushi dishes. The herb is a beautiful and aromatic garden plant with an alluring minty scent.

Traditional Medicine

Many different cultures in Asia use shiso perilla leaves and seeds. For example, Japanese cultures have used the leaves as a garnish for seafood dishes. Some cultures utilize its seeds to create oil for dyes, ink and varnish. The dried leaves also have medicinal uses for various health conditions, bone and joint strength and respiratory function.

Perilla leaves are an ancient medicinal tool for treating wind-cold disorders, including coughs, headaches and congestion, especially in children. The seed extract is warm and mild, which may play a role in its efficacy for coughs and other respiratory conditions. Experts in ancient medicine techniques believe that it also disperses stagnant qi, which helps relieve stress and possibly helps with mood disorders.

According to research, the Song dynasty was the first civilization to use the herb, as an ingredient in several medicinal formulas. However, it was during the Han dynasty that shiso perilla gained its reputation as a powerful medicinal herb. Some techniques combined shiso perilla with ingredients like cyperus, ginseng, aquilaria, citrus and agastache.

Health Benefits of Shiso Perilla

Anti-inflammatory Properties

It has been shown to possess anti-inflammatory properties, thanks to the compound rosmarinic acid. This acid can suppress the activity of inflammatory enzymes and reduce inflammation. This makes shiso perilla beneficial for those with chronic inflammatory conditions like arthritis, allergies, and asthma.

Anti-aging Properties

It is an excellent herb to consume for its anti-aging properties. It contains rosmarinic acid, a plant compound that neutralizes free radicals and helps protect the skin from damage caused by UV radiation. This compound also boosts collagen production in the skin, reducing fine lines, wrinkles, and dark spots, giving you smoother and younger-looking skin.

Rich in Antioxidants

It is loaded with antioxidants, compounds that protect the body against oxidative damage caused by free radicals. These harmful molecules can contribute to chronic diseases like cancer, heart disease, and Alzheimer’s. The antioxidants in shiso perilla, including phenolic acids and flavonoids, can help prevent these diseases.

Good for Digestion

It is a natural digestive aid and can help relieve symptoms of conditions like bloating, gas, and constipation. Its strong aroma and flavor stimulate the digestive system and encourage the production of digestive enzymes. Shiso perilla is also said to have antibacterial properties that can help combat harmful gut bacteria.

Lowers Cholesterol Levels

It is abundant in antioxidants that help to reduce inflammation and prevent the oxidation of fat molecules, one of the main culprits of high levels of cholesterol in the bloodstream. That’s bad news because high levels of cholesterol can lead to the development of a host of cardiovascular diseases. With regular consumption of shiso perilla, you can lower your cholesterol levels, reduce your risk of heart disease, and ultimately, improve your overall health.

Promotes Joint Health

The anti-inflammatory properties of Shiso Perilla come in handy again here. They reduce joint pain and inflammation, helping to manage the symptoms of various joint conditions like arthritis. The presence of rosmarinic acid, which possesses powerful anti-inflammatory benefits, makes this herb incredibly effective in promoting joint health and function.

Boosts Oral Health

IT also contains antibacterial properties that promote good oral health. The herb can help to ward off harmful bacteria that cause cavities and gum disease, making it a great natural alternative to commercial mouthwashes. The essential oils in the plant also provide a refreshing aroma that freshens breath and keeps the mouth smelling clean and healthy.

Manage Allergies

It has anti-allergic properties that help manage allergies such as hay fever, asthma, and hives. It contains a natural histamine-blocking compound that prevents histamine release, which triggers allergic reactions in the body. Incorporating Shiso Perilla in your diet can help reduce symptoms such as a runny nose, watery eyes, and difficulty breathing.

Respiratory Health

If you suffer from asthma, allergies, or other respiratory issues, shiso perilla could be your new best friend. This herb contains rosmarinic acid, which has been shown to reduce inflammation in the lungs and improve overall respiratory health. Additionally, it is a natural antihistamine, which means it can help to alleviate allergy symptoms. So the next time you feel a cough or sniffles coming on, consider reaching for some steaming shiso perilla tea.

Boosts Immunity

It is a natural immunity booster, thanks to its high vitamin C content. Vitamin C is a potent antioxidant that supports the immune system by protecting cells from damage and strengthening white blood cells. Shiso perilla also contains other immune-boosting compounds like luteolin and apigenin.

Supports Healthy Skin

It is a great all-natural remedy for a variety of skin conditions. Its high concentration of rosmarinic acid and other antioxidants can protect the skin against UV damage, inflammation, and oxidative stress. Shiso perilla can also hydrate and soothe the skin, making it a great ingredient in skin care products.

Supports Heart Health

It has been found to have cardio-protective properties that help improve heart health. It helps lower blood pressure and cholesterol levels, which are risk factors for heart disease. Shiso Perilla also has vasodilatory properties that help improve blood flow to the heart and other organs.

Helps with Mental Health

It has been found to have calming properties that help reduce anxiety and stress. It may also help improve cognitive function and memory. Shiso Perilla contains omega-3 fatty acids, which are important for brain function and development.

Benefits of Shiso Perilla

Nutritional Content

Researchers commend it for its high nutrient content, which makes it an excellent ingredient in many meals.

Healthy Fat & Protein

It is not common to find edible leaves that contain fats. However, for every 100 g, the leaves only contain 1 g of fat. Fortunately, the leaves only have unsaturated fat which, unlike saturated fat, does not increase the risk of cardiac disorders. Instead, this dietary fat promotes overall health. The oil extracted from the seeds also contains proteins and omega-3 fatty acids that promote overall health and metabolism.

Carbohydrates, Sugar & Fiber

Every 100 grams of perilla leaves contain 7 g of carbohydrates. In addition, the leaves do not contain sugar, which makes them an excellent choice for patients with high blood sugar. The leaves also contain high fiber levels, which may help with weight loss because it increases satiety. In addition, dietary fiber supports digestion and cardiac health.

Vitamins & Minerals

Shiso perilla leaves are rich in minerals, including calcium and iron. The extract also contains large quantities of vitamin C, which supports vision and cardiovascular health.

Why Try Shiso Perilla Supplements?

Advances in technology enable nutritionists and health professionals to isolate the active compounds in perilla leaves and seeds. Many scientists have tried to identify the pharmacology of various compounds in perilla, including linoleic and rosmarinic acids.

Perilla seeds contain fats and volatile oils. In fact, 60 percent of the fats in perilla seeds are omega-3 fatty acids, which can help minimize inflammation and promote cardiovascular health. Primary sources of omega-3 fatty acids include salmon, snapper and halibut and flaxseeds. Alternatives with lower concentrations of omega-3 fatty acids include walnut, canola and soy oil. However, the oil extracted from perilla seeds has the highest quantity of plant-based omega fatty acids, possibly even higher than flaxseed oil.

Perilla seed oil is also rich in policosanols, which help maintain healthy cholesterol levels in the body. Perilla leaves and seeds are also rich in rosmarinic acid that may help support digestion and minimize harmful bacteria in the mouth and GI tract.

Side Effects of Shiso Perilla

According to research, shiso perilla is possibly safe as an oral supplement for up to eight months.

Allergic Reactions

One of the most common side effects is an allergic reaction. It is related to mint and can cause allergic reactions in individuals who are allergic to mint. An allergic reaction can include skin rash, itching, swelling, and difficulty breathing. Therefore, it is important to be cautious and seek medical attention if you experience any allergic reactions.

Blood Clotting Problems

It contains a compound called estragole, which has been shown to have anticoagulant properties. Although it has many health benefits, this could be a potential problem for individuals taking blood-thinning medications. Consuming shiso perilla while taking blood-thinning medication could increase the risk of bleeding. Consult with your doctor before taking if you are on blood-thinning medications.

Possible Hormonal Effects

Shiso perilla contains compounds that may have hormonal effects on the body, such as modulating hormones, or thyroid hormones. While these effects are not well studied in humans, some animal studies suggest that shiso perilla may disrupt the reproductive system, induce uterine contractions, or alter the thyroid gland’s function. Therefore, pregnant or breastfeeding women, people with hormone-sensitive cancers, or those taking hormone replacement therapy should avoid these supplements or consume them in moderation.

Pregnancy and Breastfeeding

As with many herbs, shiso perilla has not been tested enough during pregnancy and breastfeeding. It is better to be cautious and avoid consuming it during this time to avoid any potential complications.

Interference with Medications

Shiso perilla contains a compound called rosmarinic acid. The compound has been shown to interfere with certain medications such as lithium, which is used to treat bipolar disorder. It is important to be cautious and consult with your doctor before consuming if you are on any medications.

Possible Contamination with Heavy Metals or Pesticides

Shiso perilla, like many other herbs or plants, may accumulate heavy metals or pesticides from the soil or the environment. These contaminants may cause toxic effects on the body, such as oxidative stress, DNA damage, or cancer. Therefore, it’s essential to choose high-quality products that are grown in organic or controlled environments, free from harmful chemicals or pollutants. Furthermore, it’s essential to store and handle shiso perilla properly, avoiding exposure to moisture or heat, which may cause mold or spoilage.

Other General Side Effects

Apart from the specific side effects mentioned above, shiso perilla can also cause general side effects. Common side effects include dizziness, nausea, and digestive issues. Therefore, it is important to consume in moderation, as excessive consumption could lead to unwanted side effects.


The recommended dosage for shiso perilla depends on the form and strength of the supplement or extract. Generally, it is safe to consume these extracts in amounts up to 500mg per day. However, it is always important to check with your physician before starting any new supplement or herbal regime.

Where to Buy Shiso Perilla Extract

Need a trusted place to purchase high-quality Shiso Perilla Extract? Look no more than! They are well-known for producing and distributing pure dietary supplements. Not only do they offer consumer products, but they also supply ingredients to other leading brands in the food and supplement industry. You can rest assured knowing that all products at pass through extensive manufacturing and testing procedures. Ready to give it a try? Reach out to and place your order now!


Bottom Line

Shiso perilla is an herb that predominantly grows in Asian countries, such as Japan, India, China and Korea. It is a common ingredient in traditional medicinal practices combined with other herbs to help treat various health conditions. The herb has several different health benefits and research states that it may promote cardiac, oral and digestive health. It is rich in antioxidants that may help reduce oxidative stress and fight the effects of free radicals that cause damage and disease in the body. Shiso perilla extract is also rich in vitamins, minerals, carbohydrates, proteins and fiber. It is not a cure for any medical condition. However, with a physician’s approval, it may help promote overall health.

Shiso Perilla is a true wonder plant that can provide numerous health benefits when included in your diet. From reducing cholesterol and joint pain to promoting oral health and boosting your immunity and mental health, the benefits are endless. Adding this herb to your daily routine can provide you with the natural health boost you need to stay healthy and vibrant. Try it in your salads, soups, tea, or purchase our extract, and experience the magic for yourself!

Author: James D