Ascorbyl Palmitate (Vitamin C Ester) Benefits, Side Effects and Dosage

What is Ascorbyl Palmitate (Vitamin C Ester)?

Ascorbyl palmitate is a fat-soluble antioxidant that helps maintain healthy cells in your body. It also increases the shelf life of potato chips, vegetable oils, infant formulas, drugs and cosmetics as a preservative.

However, it’s an amphipathic molecule, meaning one end is fat soluble, and the other end is water soluble. Being dual soluble allows absorption of the supplement into the cell membranes, remaining longer in your body compared to water-soluble vitamin C.

Once integrated with the cell membranes, such as the human red blood cells, ascorbyl palmitate helps protect the cells from oxidative damage. In fact, vitamin C helps bolster the body’s fat-soluble antioxidant called alpha-tocopherol (vitamin E), boosting the body’s protection against oxidization caused by free radicals (x, x).

Free radicals occur from external factors like smoking, diet, UV light and pollution. And so, the harmful effects of free radicals or oxidation in your body can damage the DNA in your cells, cellular proteins, cell membranes and collagen. The fat-soluble supplement helps neutralize the free radicals, so your body remains healthy (x).

Ascorbyl palmitate in oral supplements contributes to the ascorbic acid content of the nutritional supplement. As an antioxidant, manufacturers add it to topical preparations for the skin thanks to it being more stable than water-soluble forms of vitamin C.

Also, vitamin C ester may confuse you into thinking ascorbyl palmitate is Ester-C, but that is not the case. These two supplements are different. The significant difference is ascorbyl palmitate is lipid soluble, so it penetrates your skin better than other water-soluble forms of vitamin C and L-ascorbic acid. As a fat-soluble component, it stores in the fatty tissues of your body, lasting longer in the body compared to water-soluble vitamin C (x).

If you are interested in taking ascorbyl palmitate or any new supplement, talk to your physician first to see if it fits your health regime.

Ascorbyl Palmitate (Vitamin C Ester) Benefits


One property that makes ascorbyl palmitate so powerful is its antioxidant capabilities, thanks to it being a fat-soluble vitamin C. On a molecular level, antioxidants are substances that neutralize free radicals. Free radicals are harmful and uncharged molecules drifting unstable within your body. Such a condition in the body creates toxic by-products of oxygen metabolism, free radicals, which are reactive, destructive and short-lived.

Free radicals can create severe health concerns and disrupt your routine body system if unstopped. They trigger “oxidative stress,” an unhealthy state of affairs where free radicals wreak havoc faster than your body can prevent the devastation. Here, antioxidants from ascorbyl palmitate may help, therefore preventing diseases.

So much research reinforces the benefits of antioxidants as components that rescue your body from oxidative stress. These biological agents donate an electron to demolish the chaotic chain reactions caused by free radicals. Antioxidant enzymes can also generate inside your body, which the ascorbyl palmitate supports. In fact, nutrient-rich fresh fruits and vegetables and cooking spices contain them as well. Today, it’s most beneficial to use health supplements packed with antioxidants to ward off free radicals (x).

Fortifies the Immune System

Advanced technology has enabled manufacturers to make a fat-soluble vitamin C called ascorbyl palmitate. In fact, this supplement has a more extended bioavailability and absorption into the body and is more potent than water-soluble vitamin Cs.

You’ve probably heard that food containing vitamin C enhances your body’s immunity and increases its defenses against microorganisms that cause diseases and infections. ascorbyl palmitate does that and more because it’s a fat-soluble vitamin, boosting your immune system even more. The supplement stimulates thymus lymphocytes or T-cells. These are particular white blood cells or leukocytes that develop from the thymus organ, playing a significant role in the body’s immune response and the adaptive immune response (x).

Vitamin C also helps increase interferons, an essential antiviral protein produced by cells to stop the invasion of a virus and prevents replication of the virus (x). In other words, ascorbyl palmitate has the components to boost your immune system to help fight and prevent infections and diseases.

Supports Healthy Skin, Tissue and Cartilage

Ascorbyl palmitate may help increase collagen production in your body, thus supporting healthy skin, cartilage and tissue. The supplement also helps stimulate the healing of scar tissues and encourages faster recovery from dislocated joints and fractures of the bones (x).

The National Library of Medicine publicized a study that proved ascorbyl palmitate and ascorbic acid together can help the body synthesize collagen by mitigating calcium and sodium blockers. In fact, ascorbyl palmitate can lessen the blockers, stimulate collagen and enable the body to absorb collagen (x).

Ever since science discovered that vitamin C prevented and treated scurvy, comprehensive studies have proven that vitamin C (ascorbyl palmitate) benefits the skin.

Besides being an antioxidant and preservative in cosmetics, it also helps to keep your skin looking young by protecting it from the sun. The vitamin reverses the damage and protects your skin from the sun’s ultraviolet (UV) rays.

A study investigated the ascorbyl palmitate effectiveness in reversing sun-damaged skin. They purposely applied UA irradiation to pig skin, a toxic substance that causes free radicals to form, producing damaged skin or potential skin cancer. Then they applied ascorbyl palmitate topical to the damaged pig skin. The results were positive, decreasing the level of formation of free radicals, proving that vitamin C, when applied to damaged skin, can reduce the emergence of free radicals (x).

Studies also suggest that vitamin C may help you if you are antioxidant-deficient or have increased levels of oxidative stress, such as diabetic, smokers and elderly people (x).

Promotes Less Joint Pain

According to a study, ascorbyl palmitate supports your body’s joint health thanks to the fact that the supplement carries ascorbate into the body’s neutral (nerve) tissues. The ascorbyl palmitate can cross biological barriers and satisfy the tissues demand for ascorbate (x).

Vitamin C may help with joint pain based on clinical studies that show administering the supplement decreases patients’ symptoms of chronic pain in the wrists, ankles, knees and lower limb pain. The researchers also showed that the cause of chronic pain is a deficiency in vitamin C, similar to scurvy (x).

Additionally, persistent musculoskeletal pain that affects ligaments, tendons, bones, joints and muscles is treatable with vitamin C for positive results. A study investigated supplementing with vitamin C for patients who had wrist and ankle surgery relating to fractured bones. The results showed that daily administration of the supplement decreased pain following the surgery (x).

Another report shows that people in need of joint replacement surgery because of osteoarthritis who took vitamin C for 50 days before surgery showed decreased pain compared to those who took anti-inflammatory drugs (x).

Also, those who experience pain associated with rheumatoid arthritis and take vitamin C intravenously experience less pain (x).

Supports Vascular Health

Evidence shows that besides being an antioxidant, vitamin C helps prevent plaque instability in atherosclerosis formation of fatty plaques in your arteries. The Nurses’ Healthy Study, lasting 16 years and involving over 85,000 females, increased their vitamin C intake as a supplement, and diet lowered their chances of coronary heart disease (xx).

Another involving over 20,000 adults showed concentrations of vitamin C lowered the potential risk of strokes by 42 percent. A study of over 293,000 free of coronary heart disease took an average of 700 mg a day of vitamin C and had a 25 percent lower risk of heart disease (x).

If you have a history of cardiovascular disease in your family, talk to your healthcare provider about increasing your antioxidants, like vitamin C.

Helps Boost Healthy Metabolism

Your body needs vitamin C to produce complex molecules like collagen, L-carnitine (involved in metabolism) and certain neurotransmitters. ascorbyl palmitate also concerns itself in the metabolism of protein (x).

Research reports that vitamin C aids in the metabolism of collagen and even some hormones. Your body needs high levels of the supplement maintained for effective results. Thus, ascorbyl palmitate can do that for your body since it’s a fat-soluble vitamin C. These factors also support its use in anti-aging treatments and serums (x).

Anti-Aging Supplement

Because ascorbyl palmitate helps with metabolism and delivers antioxidants faster, vitamin C prevents cellular aging. The component inhibits the cross-linking of collagen, oxidation cell membranes, and proteins. Additionally, the supplement helps metabolize antioxidant alpha-tocopherol. The ester C vitamin keeps your body young (x).

Vitamin C plays a role in the physiological occurrence of stem cell differentiation and respiratory development. The growing recognition that this includes aging-related diseases, like heart disease, cancer, and neural degeneration. Studies support this aspect of vitamin C, showing a wide range of therapeutic benefits in treating aging-related degenerative diseases. These findings relate to the fact that ascorbyl palmitate reduces the oxidation in your body that causes these degenerative diseases (x).

Slow Down AMA and Cataracts

Studies also show that vitamin C, combined with other supplements, may help slow down age-related macular degeneration (AMD) and cataracts. An extensive study with older adults at high risk of AMD took 500 mg vitamin C, 400 IU vitamin E, 80 mg zinc, 2 mg copper and 15 mg beta-carotene for about six years. The results showed they had a lower chance of having advanced AMD. Also, they experienced less vision loss than older adults who didn’t take the dietary supplements (x).

Contributes to Healthy Teeth and Bones

Since having a deficiency in vitamin C causes bleeding, swollen gums and loosening or loss of teeth, you can correlate that vitamin C is good for your teeth. Bone health also applies to this concept. Such a deficiency can cause weak and brittle bones. Other studies show that vitamin C can help prevent osteoporosis (xx).

The studies supporting vitamin C intake relate to maintaining many cell types in your body. Lack of the supplement leads to scurvy, along with other ailments, leads to gum problems, bone pain and impaired wound healing.

Vitamin C is integral in developing and maintaining bone tissues and skeletal bones. That way, your body avoids unnecessary bone fractures and osteoporosis, helping the bones heal when injured. Overall, the metabolism of the supplement is essential (x).

Thus, if you’re undergoing treatment for diabetes, smoking or are elderly, then you must track your vitamin C intake. That way, you prevent a deficiency in the supplement, causing other health concerns (x).

You must discuss this with your physician in case other factors are in play.

Helps with Skin Health

The antioxidant properties of vitamin C and its role in the metabolism of collagen can help maintain the health of your skin. The supplement also helps with wound healing thanks to the collagen. Studies prove that vitamin C speeds up healing in people who have the supplement in their systems (x).

Pick up any skin lotion, serum or scrub, and if it promotes glowing skin, it most likely contains ascorbyl palmitate. Some consider it a beauty game-changer, working with vitamin E to reduce wrinkles, sagging skin, discoloration and signs of aging. The supplement also helps reduce the damage caused by UV exposures (xx).

Recommend Dosage of Ascorbyl Palmitate

The dosage for taking ascorbyl palmitate (vitamin C ester) as a dietary supplement is 500 mg four times daily. Or take the amount as directed by your doctor. This recommendation does not include intake of foods with high levels of vitamin C or other food sources of vitamin C. Supplementing too much vitamin C can cause these symptoms:

  • Diarrhea
  • Nausea
  • Vomiting
  • Heartburn
  • Stomach Pain
  • Headache
  • Insomnia

Possible Side Effects of Ascorbyl Palmitate

Although vitamin C is safe to take in the main, there are some potential side effects:

  • Upset stomach during or after eating
  • Feeling faint
  • Redness and warm feeling of the skin or flushing
  • Headache
  • Nausea, vomiting or diarrhea

Where to Buy Ascorbyl Palmitate (Vitamin C Ester)?

You can purchase Ascorbyl Palmitate (Vitamin C Ester) at The company is an industry-leading manufacturer and distributor of pure dietary supplements. is not just a consumer brand. It also supplies pure ingredients to other brands that distribute food and other supplement products. All products at are manufactured and tested according to current and proper manufacturing practices.

Are you interested in trying ascorbyl palmitate as a dietary supplement for its potential to support healthy teeth and bones, healthy skin, anti-aging and antioxidant properties and metabolism of vital nutritional components? Contact to place an order today.

The Bottom Line

Ascorbyl palmitate (vitamin C ester) is the only fat-soluble and water-soluble vitamin C, helping to maintain healthy cells in your body. In fact, manufacturers use it as a preservative because of its antioxidant properties.

Both water-soluble and fat-soluble allow more reliable absorption of the supplement into the cell membranes. There it remains longer than water-soluble vitamin C.

Once integrated with the cell membranes, the ascorbyl palmitate helps protect the cells from oxidative damage. Vitamin C helps strengthen the body’s fat-soluble antioxidant called alpha-tocopherol (vitamin E), advancing the body’s protection even more against oxidization caused by free radicals. The fat-soluble supplement helps neutralize the free radicals, so your body remains healthy.

Ascorbyl palmitate helps the body maintain healthy teeth, bones and skin. It also supports the body when under treatment for diabetes, cancer and heart disease, maintaining extensive reinforcement thanks to its fat-soluble aspect.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Author: BulkSupplements Staff